Hypoxia inducible-factor 1 alpha regulates neutrophil recruitment during fungal-elicited granulomatous inflammation

Hypoxia inducible-factor 1 alpha regulates neutrophil recruitment during fungal-elicited granulomatous inflammation

Chronic pulmonary aspergillosis (CPA) is a devastating disease with increasing prevalence worldwide. The characteristic granulomatous-like inflammation poses as the major setback to effective antifungal therapies by limiting drug access to fungi. These inflammatory lung structures are reported to be...

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Bibliographic Details
Main Authors: Sara da Silva-Ferreira, Cláudio Duarte-Oliveira, Daniela Antunes, Catarina Barbosa-Matos, Ana Mendes-Frias, Egídio Torrado, Sandra Costa, Ricardo Silvestre, Cristina Cunha, Agostinho Carvalho
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
hypoxia inducible-factor 1 alpha
Aspergillus
granuloma
neutrophils
chronic fungal disease
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1005839/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.1005839/full

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