Post-click labeling enables highly accurate single cell analyses of glucose uptake ex vivo and in vivo

Abstract Cellular glucose uptake is a key feature reflecting metabolic demand of cells in physiopathological conditions. Fluorophore-conjugated sugar derivatives are widely used for monitoring glucose transporter (GLUT) activity at the single-cell level, but have limitations in in vivo applications....

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Bibliographic Details
Main Authors: Masaki Tsuchiya, Nobuhiko Tachibana, Itaru Hamachi
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-06164-y