Trypanosomal mitochondrial intermediate peptidase does not behave as a classical mitochondrial processing peptidase.

Upon their translocation into the mitochondrial matrix, the N-terminal pre-sequence of nuclear-encoded proteins undergoes cleavage by mitochondrial processing peptidases. Some proteins require more than a single processing step, which involves several peptidases. Down-regulation of the putative Tryp...

Full description

Bibliographic Details
Main Authors: Priscila Peña-Diaz, Jan Mach, Eva Kriegová, Pavel Poliak, Jan Tachezy, Julius Lukeš
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5919513?pdf=render