Directional migration of recirculating lymphocytes through lymph nodes via random walks.

Naive T lymphocytes exhibit extensive antigen-independent recirculation between blood and lymph nodes, where they may encounter dendritic cells carrying cognate antigen. We examine how long different T cells may spend in an individual lymph node by examining data from long term cannulation of blood...

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Bibliographic Details
Main Authors: Niclas Thomas, Lenka Matejovicova, Wichat Srikusalanukul, John Shawe-Taylor, Benny Chain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3447944?pdf=render