Novel DNA methylation biomarkers in stool and blood for early detection of colorectal cancer and precancerous lesions

Novel DNA methylation biomarkers in stool and blood for early detection of colorectal cancer and precancerous lesions

Abstract Background Early detection and prevention of precancerous lesions can significantly reduce the morbidity and mortality of colorectal cancer (CRC). Here, we developed new candidate CpG site biomarkers for CRC and evaluated the diagnostic value of their expression in blood and stool samples o...

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Bibliographic Details
Main Authors: Yuguang Shen, Dongyang Wang, Tianli Yuan, Hongsheng Fang, Chen Zhu, Juan Qin, Xiaojing Xu, Cheng Zhang, Jiahua Liu, Yuanruohan Zhang, Zhoujin Wen, Jian Tang, Zheng Wang
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Clinical Epigenetics
Subjects:
DNA methylation biomarkers
Colorectal cancer
Advanced adenoma
Early detection
Online Access:https://doi.org/10.1186/s13148-023-01443-7

Internet

https://doi.org/10.1186/s13148-023-01443-7

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