Extracellular vesicles secreted by Brugia malayi microfilariae modulate the melanization pathway in the mosquito host

Abstract Vector-borne, filarial nematode diseases cause significant disease burdens in humans and domestic animals worldwide. Although there is strong direct evidence of parasite-driven immunomodulation of mammalian host responses, there is less evidence of parasite immunomodulation of the vector ho...

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Bibliographic Details
Main Authors: Hannah J. Loghry, Hyeogsun Kwon, Ryan C. Smith, Noelle A. Sondjaja, Sarah J. Minkler, Sophie Young, Nicolas J. Wheeler, Mostafa Zamanian, Lyric C. Bartholomay, Michael J. Kimber
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-35940-9