Multicopy Suppressor Analysis of Strains Lacking Cytoplasmic Peptidyl-Prolyl <i>cis/trans</i> Isomerases Identifies Three New PPIase Activities in <i>Escherichia coli</i> That Includes the DksA Transcription Factor

Multicopy Suppressor Analysis of Strains Lacking Cytoplasmic Peptidyl-Prolyl <i>cis/trans</i> Isomerases Identifies Three New PPIase Activities in <i>Escherichia coli</i> That Includes the DksA Transcription Factor

Consistent with a role in catalyzing rate-limiting step of protein folding, removal of genes encoding cytoplasmic protein folding catalysts belonging to the family of peptidyl-prolyl <i>cis/trans</i> isomerases (PPIs) in <i>Escherichia coli</i> confers conditional lethality....

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Bibliographic Details
Main Authors: Pawel Wojtkiewicz, Daria Biernacka, Patrycja Gorzelak, Anna Stupak, Gracjana Klein, Satish Raina
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
prolyl isomerase
protein folding
RNA polymerase
DksA
heat shock proteins
DnaK/J
Online Access:https://www.mdpi.com/1422-0067/21/16/5843

Internet

https://www.mdpi.com/1422-0067/21/16/5843

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