Identification of Two Distinct Immune Subtypes in Hepatitis B Virus (HBV)-Associated Hepatocellular Carcinoma (HCC)

Identification of Two Distinct Immune Subtypes in Hepatitis B Virus (HBV)-Associated Hepatocellular Carcinoma (HCC)

HBV is the most common risk factor for HCC development, accounting for almost 50% of cases worldwide. Despite significant advances in immunotherapy, there is limited information on the HBV-HCC tumor microenvironment (TME), which may influence the response to checkpoint inhibitors. Here, we character...

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Bibliographic Details
Main Authors: Davide De Battista, Rylee Yakymi, Evangeline Scheibe, Shinya Sato, Hannah Gerstein, Tovah E. Markowitz, Justin Lack, Roberto Mereu, Cristina Manieli, Fausto Zamboni, Patrizia Farci
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cancers
Subjects:
hepatocellular carcinoma
hepatitis B virus
RNA-sequencing
tumor microenvironment
immune checkpoints in HCC
CTLA-4 expression in HCC
Online Access:https://www.mdpi.com/2072-6694/16/7/1370

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https://www.mdpi.com/2072-6694/16/7/1370

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