The Influence of Formulation and Manufacturing Process Parameters on the Characteristics of Lyophilized Orally Disintegrating Tablets

The Influence of Formulation and Manufacturing Process Parameters on the Characteristics of Lyophilized Orally Disintegrating Tablets

Gelatin is a principal excipient used as a binder in the formulation of lyophilized orally disintegrating tablets. The current study focuses on exploiting the physicochemical properties of gelatin by varying formulation parameters to determine their influence on orally disintegrating tablet (ODT) ch...

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Bibliographic Details
Main Authors: Marina Levina, Afzal R. Mohammed, Yvonne Perrie, Ali Rajabi-Siahboomi, Rhys J. Jones
Format: Article
Language:English
Published: MDPI AG 2011-07-01
Series:Pharmaceutics
Subjects:
freeze-drying
orally disintegrating tablets
gelatin
pH
ionic strength
milling
Online Access:http://www.mdpi.com/1999-4923/3/3/440/

Internet

http://www.mdpi.com/1999-4923/3/3/440/

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