Presence of Viral Genome in Urine and Development of Hematuria and Pathological Changes in Kidneys in Common Marmoset (Callithrix jacchus) after Inoculation with Dengue Virus

Presence of Viral Genome in Urine and Development of Hematuria and Pathological Changes in Kidneys in Common Marmoset (Callithrix jacchus) after Inoculation with Dengue Virus

Common marmosets (Callithrix jacchus) developed high levels of viremia, clinical signs including fever, weight loss, a decrease in activity and hematuria upon inoculation with dengue virus (DENV). Presence of DENV genome in urine samples and pathological changes in kidneys were examined in the prese...

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Bibliographic Details
Main Authors: Hirofumi Akari, Ichiro Kurane, Mikako Ito, Tomohiko Takasaki, Shigeru Tajima, Tomoyuki Yoshida, Akatsuki Saito, Yuko Katakai, Takanori Hirayama, Shinichiro Nakamura, Tsutomu Omatsu, Meng Ling Moi
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:Pathogens
Subjects:
dengue virus
animal model
marmoset
urine
hematuria
kidney
Online Access:http://www.mdpi.com/2076-0817/2/2/357

Internet

http://www.mdpi.com/2076-0817/2/2/357

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