Gliopathy of Demyelinating And Non-Demyelinating Strains Of Mouse Hepatitis Virus.

Gliopathy of Demyelinating And Non-Demyelinating Strains Of Mouse Hepatitis Virus.

Demyelination in the central nervous system induced by neurovirulent strains of Mouse Hepatitis Virus (MHV) is mediated by the viral spike glycoprotein, but it is not clear whether the mechanism of this disease pathology involves direct viral infection of oligodendrocytes. Detailed studies of glial...

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Bibliographic Details
Main Authors: Lawrence Charles Kenyon, Kaushiki eBiswas, Kenneth eShindler, Manasi eNabar, Marjorie eStout, Susan T Hingley, Judith B Grinspan, Jayasri eDas Sarma
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Astrocytes
Multiple Sclerosis
demyelination
oligodendrocytes
Mouse hepatitis virus
Virus host attachement Spike protein
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00488/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00488/full

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