Sphingosine-1-Phosphate Signaling in Ischemic Stroke: From Bench to Bedside and Beyond

Sphingosine-1-Phosphate Signaling in Ischemic Stroke: From Bench to Bedside and Beyond

Sphingosine-1-phosphate (S1P) signaling is being increasingly recognized as a strong modulator of immune cell migration and endothelial function. Fingolimod and other S1P modulators in ischemic stroke treatment have shown promise in emerging experimental models and small-scale clinical trials. In th...

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Bibliographic Details
Main Authors: Shuo-Qi Zhang, Jun Xiao, Man Chen, Luo-Qi Zhou, Ke Shang, Chuan Qin, Dai-Shi Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
sphingosine-1-phosphate
ischemic stroke
fingolimod
neuroprotective agent
translational research
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.781098/full

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https://www.frontiersin.org/articles/10.3389/fncel.2021.781098/full

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