Neonatal priming and infancy boosting with a novel respiratory syncytial virus vaccine induces protective immune responses without concomitant respiratory disease upon RSV challenge

Neonatal priming and infancy boosting with a novel respiratory syncytial virus vaccine induces protective immune responses without concomitant respiratory disease upon RSV challenge

Although respiratory syncytial virus (RSV) infection in infants and young children is a global public health issue, development of a safe RSV vaccine has been impeded by formalin-inactivated RSV-enhanced respiratory disease (ERD). In developing a safer yet effective RSV vaccine for children, a strat...

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Bibliographic Details
Main Authors: Shuren Zhang, Gan Zhao, Caixia Su, Chaofan Li, Xian Zhou, Weidong Zhao, Yiwei Zhong, Zhonghuai He, Haichang Peng, Aihua Dong, Bin Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-03-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
rsv
vaccine
vaccine enhanced disease
g protein
csa
protection
neonate protection
Online Access:http://dx.doi.org/10.1080/21645515.2019.1671134

Internet

http://dx.doi.org/10.1080/21645515.2019.1671134

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