TLR8 signaling enhances tumor immunity by preventing tumor‐induced T‐cell senescence

TLR8 signaling enhances tumor immunity by preventing tumor‐induced T‐cell senescence

Abstract Accumulating evidence suggests the immunosuppressive microenvironments created by malignant tumors represent a major obstacle for effective anti‐tumor immunity. A better understanding of the suppressive mechanisms mediated by tumor microenvironments and the development of strategies to reve...

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Bibliographic Details
Main Authors: Jian Ye, Chunling Ma, Eddy C Hsueh, Jie Dou, Wei Mo, Shuai Liu, Bing Han, Yi Huang, Yanping Zhang, Mark A Varvares, Daniel F Hoft, Guangyong Peng
Format: Article
Language:English
Published: Springer Nature 2014-10-01
Series:EMBO Molecular Medicine
Subjects:
immunosenescence
regulatory T cells
toll‐like receptor
tumor immunity
tumor microenvironment
Online Access:https://doi.org/10.15252/emmm.201403918

Internet

https://doi.org/10.15252/emmm.201403918

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