hSSB2 (NABP1) is required for the recruitment of RPA during the cellular response to DNA UV damage

Abstract Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, eukaryotic cells have multiple pathways to efficiently detect, signal and repair DNA damage. One common form of exogenous DNA damage comes from ultraviolet B (UVB) radiation. UVB generates cyclobutane...

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Bibliographic Details
Main Authors: Didier Boucher, Ruvini Kariawasam, Joshua Burgess, Adrian Gimenez, Tristan E. Ocampo, Blake Ferguson, Ali Naqi, Graeme J. Walker, Emma Bolderson, Roland Gamsjaeger, Kenneth J. O’Byrne, Liza Cubeddu, Kum Kum Khanna, Derek J. Richard
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-99355-0