Ex Vivo Alloanergization with Belatacept: A Strategy to Selectively Modulate Alloresponses after Transplantation

Ex vivo alloanergization of human immune cells, via allostimulation in the presence of costimulatory blockade with either a combination of anti-B7.1 and anti-B7.2 antibodies or first-generation cytotoxic T-lymphocyte antigen 4-immunoglobulin (CTLA4-Ig), induces alloantigen-specific hyporesponsivenes...

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Bibliographic Details
Main Authors: Jeff K. Davies, Christine M. Barbon, Annie Voskertchian, Lee M. Nadler, Eva C. Guinan
Format: Article
Language:English
Published: SAGE Publishing 2012-09-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X637479