In vitro and in vivo efficacy of a Rift Valley fever virus vaccine based on pseudovirus

In vitro and in vivo efficacy of a Rift Valley fever virus vaccine based on pseudovirus

Rift Valley fever virus (RVFV), a recognized category A priority pathogen, causes large outbreaks of Rift Valley fever with some fatalities in humans in humans and huge economic losses in livestock. As wild-type RVFV must be handled in BSL-3 or BSL-4 laboratories, we constructed a high-titer vesicul...

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Bibliographic Details
Main Authors: Jian Ma, Ruifeng Chen, Weijin Huang, Jianhui Nie, Qiang Liu, Youchun Wang, Xiaoming Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2019-10-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
rift valley fever virus
pseudovirus
neutralizing antibody
mouse model
site mutation
dna vaccine
Online Access:http://dx.doi.org/10.1080/21645515.2019.1627820

Internet

http://dx.doi.org/10.1080/21645515.2019.1627820

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