Hypothermic Oxygenated Machine Perfusion Promotes Mitophagy Flux against Hypoxia-Ischemic Injury in Rat DCD Liver

Hypothermic Oxygenated Machine Perfusion Promotes Mitophagy Flux against Hypoxia-Ischemic Injury in Rat DCD Liver

Hypothermic oxygenated machine perfusion (HOPE) can enhance organ preservation and protect mitochondria from hypoxia-ischemic injury; however, an understanding of the underlying HOPE mechanism that protects mitochondria is somewhat lacking. We hypothesized that mitophagy may play an important role i...

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Bibliographic Details
Main Authors: Jia Luo, Yiqing Hu, Yinbiao Qiao, Haoyu Li, Jiacheng Huang, Kangdi Xu, Li Jiang, Hao Wu, Xiaoyi Hu, Junjun Jia, Lin Zhou, Haiyang Xie, Jianhui Li, Shusen Zheng
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
HOPE
DCD liver
mitophagy
hypoxia-ischemic injury
organ protection
Online Access:https://www.mdpi.com/1422-0067/24/6/5403

Internet

https://www.mdpi.com/1422-0067/24/6/5403

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