The cytosolic domain of Pex22p stimulates the Pex4p-dependent ubiquitination of the PTS1-receptor.

The cytosolic domain of Pex22p stimulates the Pex4p-dependent ubiquitination of the PTS1-receptor.

Peroxisomal biogenesis is an ubiquitin-dependent process because the receptors required for the import of peroxisomal matrix proteins are controlled via their ubiquitination status. A key step is the monoubiquitination of the import receptor Pex5p by the ubiquitin-conjugating enzyme (E2) Pex4p. This...

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Bibliographic Details
Main Authors: Fouzi El Magraoui, Andreas Schrötter, Rebecca Brinkmeier, Lena Kunst, Thomas Mastalski, Thorsten Müller, Katrin Marcus, Helmut E Meyer, Wolfgang Girzalsky, Ralf Erdmann, Harald W Platta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4146569?pdf=render

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http://europepmc.org/articles/PMC4146569?pdf=render

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