Interferon lambda rs368234815 ΔG/ΔG is associated with higher CD4+:CD8+ T-cell ratio in treated HIV-1 infection

Interferon lambda rs368234815 ΔG/ΔG is associated with higher CD4+:CD8+ T-cell ratio in treated HIV-1 infection

Abstract Background The objectives of this study were to investigate the relationships between polymorphisms at the interferon lambda (IFNL) locus and CD4+:CD8+ ratio normalisation in people living with HIV (PLWH) on effective antiretroviral therapy (ART); and to examine whether these polymorphisms...

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Bibliographic Details
Main Authors: Inês T. Freitas, Willard Tinago, Hirofumi Sawa, Julie McAndrews, Brenda Doak, Charlotte Prior-Fuller, Gerard Sheehan, John S. Lambert, Eavan Muldoon, Aoife G. Cotter, William W. Hall, Patrick W. G. Mallon, Michael J. Carr
Format: Article
Language:English
Published: BMC 2020-04-01
Series:AIDS Research and Therapy
Subjects:
HIV
Interferon lambda
T-cells
CD4+
CD8+
Online Access:http://link.springer.com/article/10.1186/s12981-020-00269-0

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http://link.springer.com/article/10.1186/s12981-020-00269-0

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