Construction of a T7 phage display nanobody library for bio-panning and identification of chicken dendritic cell-specific binding nanobodies

Abstract Dendritic cells (DCs) are the antigen-presenting cells that initiate and direct adaptive immune responses, and thus are critically important in vaccine design. Although DC-targeting vaccines have attracted attention, relevant studies on chicken are rare. A high diversity T7 phage display na...

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Bibliographic Details
Main Authors: Hai Xu, Ling Li, Bihua Deng, Weiming Hong, Ruiting Li, Zijie Guo, Jibo Hou, Roshini Govinden, Hafizah Y. Chenia
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-16378-x