Astrocyte interferon-gamma signaling dampens inflammation during chronic central nervous system autoimmunity via PD-L1

Astrocyte interferon-gamma signaling dampens inflammation during chronic central nervous system autoimmunity via PD-L1

Abstract Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease of the central nervous system (CNS). Infiltrating inflammatory immune cells perpetuate demyelination and axonal damage in the CNS and significantly contribute to pathology and clinical deficits. While the cytokine inte...

Full description

Bibliographic Details
Main Authors: Brandon C. Smith, Rachel A. Tinkey, Orion D. Brock, Arshiya Mariam, Maria L. Habean, Ranjan Dutta, Jessica L. Williams
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Journal of Neuroinflammation
Subjects:
Multiple sclerosis
Astrocyte
Interferon
Online Access:https://doi.org/10.1186/s12974-023-02917-4

Internet

https://doi.org/10.1186/s12974-023-02917-4

Similar Items