Tail-vein injection of MSC-derived small extracellular vesicles facilitates the restoration of hippocampal neuronal morphology and function in APP / PS1 mice

Tail-vein injection of MSC-derived small extracellular vesicles facilitates the restoration of hippocampal neuronal morphology and function in APP / PS1 mice

Abstract Mesenchymal stem-cell-derived small extracellular vesicles (MSC-EVs), as a therapeutic agent, have shown great promise in the treatment of neurological diseases. To date, the neurorestorative effects and underlying mechanism of MSC-EVs in Alzheimer’s disease (AD) are not well known. Herein,...

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Bibliographic Details
Main Authors: Han Wang, Yuqi Liu, Junchen Li, Tian Wang, Yue Hei, Huiming Li, Xue Wang, Lina Wang, Ruijing Zhao, Weiping Liu, Qianfa Long
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00620-y

Internet

https://doi.org/10.1038/s41420-021-00620-y

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