Fibronectin as a multiregulatory molecule crucial in tumor matrisome: from structural and functional features to clinical practice in oncology

Fibronectin as a multiregulatory molecule crucial in tumor matrisome: from structural and functional features to clinical practice in oncology

Abstract Deciphering extracellular matrix (ECM) composition and architecture may represent a novel approach to identify diagnostic and therapeutic targets in cancer. Among the ECM components, fibronectin and its fibrillary assembly represent the scaffold to build up the entire ECM structure, deeply...

Full description

Bibliographic Details
Main Authors: Sheila Spada, Annalisa Tocci, Francesca Di Modugno, Paola Nisticò
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Fibronectin
Fibrillogenesis
Extracellular matrix
Actin cytoskeleton
Cancer-associated fibroblasts
Metastasis
Online Access:https://doi.org/10.1186/s13046-021-01908-8

Internet

https://doi.org/10.1186/s13046-021-01908-8

Similar Items