Whole Genome Sequencing Revealed Inherited Rare Oligogenic Variants Contributing to Schizophrenia and Major Depressive Disorder in Two Families

Whole Genome Sequencing Revealed Inherited Rare Oligogenic Variants Contributing to Schizophrenia and Major Depressive Disorder in Two Families

Schizophrenia and affective disorder are two major complex mental disorders with high heritability. Evidence shows that rare variants with significant clinical impacts contribute to the genetic liability of these two disorders. Also, rare variants associated with schizophrenia and affective disorder...

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Bibliographic Details
Main Authors: I-Hang Chung, Yu-Shu Huang, Ting-Hsuan Fang, Chia-Hsiang Chen
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
schizophrenia
major depression
heritability
genetics
rare mutations
oligogenic
Online Access:https://www.mdpi.com/1422-0067/24/14/11777

Internet

https://www.mdpi.com/1422-0067/24/14/11777

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