Mechanisms of Progranulin Action and Regulation in Genitourinary Cancers

The growth factor progranulin has emerged in recent years as a critical regulator of transformation in several cancer models, including breast cancer, glioblastomas, leukemias and hepatocellular carcinomas. Several laboratories, including ours, have also demonstrated an important role of progranulin...

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Bibliographic Details
Main Authors: Ryuta Tanimoto, Koujung G Lu, Shi-Qiong Xu, Simone Buraschi, Antonino Belfiore, Renato V Iozzo, Andrea Morrione
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00100/full