Pellino 3 promotes the colitis‐associated colorectal cancer through suppression of IRF4‐mediated negative regulation of TLR4 signalling

The incidence of colitis‐associated colorectal cancer (CAC) has increased due to a high‐nutrient diet, increased environmental stimuli and inherited gene mutations. To adequately treat CAC, drugs should be developed by identifying novel therapeutic targets. E3 ubiquitin‐protein ligase pellino homolo...

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Bibliographic Details
Main Authors: Young‐Mi Kim, Hye‐Youn Kim, Huyen Trang Ha Thi, Jooyoung Kim, Young Jae Lee, Seong‐Jin Kim, Suntaek Hong
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Molecular Oncology
Subjects:
Online Access:https://doi.org/10.1002/1878-0261.13475