Palmitic acid activates NLRP3 inflammasome and induces placental inflammation during pregnancy in mice

Palmitic acid activates NLRP3 inflammasome and induces placental inflammation during pregnancy in mice

Maternal obesity is one of the major risk factors for pregnancy complications and is associated with low-grade chronic systemic inflammation due to higher levels of pro-inflammatory cytokines such as interleukin (IL)-1β. Pregnant women with obesity have abnormal lipid profiles, characterized by high...

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Bibliographic Details
Main Authors: Michiya SANO, Sayaka SHIMAZAKI, Yasuaki KANEKO, Tadayoshi KARASAWA, Masafumi TAKAHASHI, Akihide OHKUCHI, Hironori TAKAHASHI, Akira KUROSAWA, Yasushi TORII, Hisataka IWATA, Takehito KUWAYAMA, Koumei SHIRASUNA
Format: Article
Language:English
Published: The Society for Reproduction and Development 2020-02-01
Series:The Journal of Reproduction and Development
Subjects:
inflammation
nlrp3 inflammasome
placenta
pregnancy
Online Access:https://www.jstage.jst.go.jp/article/jrd/66/3/66_2020-007/_pdf/-char/en

Internet

https://www.jstage.jst.go.jp/article/jrd/66/3/66_2020-007/_pdf/-char/en

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