Rac3 induces a molecular pathway triggering breast cancer cell aggressiveness: differences in MDA-MB-231 and MCF-7 breast cancer cell lines

Rac3 induces a molecular pathway triggering breast cancer cell aggressiveness: differences in MDA-MB-231 and MCF-7 breast cancer cell lines

<p>Abstract</p> <p>Background</p> <p>Rho GTPases are involved in cellular functions relevant to cancer. The roles of RhoA and Rac1 have already been established. However, the role of Rac3 in cancer aggressiveness is less well understood.</p> <p>Methods</p...

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Bibliographic Details
Main Authors: Gest Caroline, Joimel Ulrich, Huang Limin, Pritchard Linda-Louise, Petit Alexandre, Dulong Charlène, Buquet Catherine, Hu Chao-Quan, Mirshahi Pezhman, Laurent Marc, Fauvel-Lafève Françoise, Cazin Lionel, Vannier Jean-Pierre, Lu He, Soria Jeannette, Li Hong, Varin Rémi, Soria Claudine
Format: Article
Language:English
Published: BMC 2013-02-01
Series:BMC Cancer
Subjects:
Breast cancer
Cancer aggressiveness
Rac3 GTPases
ERK
NF-κB
Online Access:http://www.biomedcentral.com/1471-2407/13/63

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http://www.biomedcentral.com/1471-2407/13/63

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