Sulfasalazine Sensitizes Polyhematoporphyrin-Mediated Photodynamic Therapy in Cholangiocarcinoma by Targeting xCT

Cholangiocarcinoma (CCA), which is highly malignant, shows a relatively poor prognosis, due to the insensitivity of the tumour to chemotherapy and radiotherapy. Photodynamic therapy (PDT) has become a promising palliative therapeutic option for patients with unresectable cholangiocarcinoma (CCA), wh...

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Bibliographic Details
Main Authors: Yan-Wen Zheng, Xiong-Ying Miao, Li Xiong, Bo Chen, Fan-Hua Kong, Jiang-Jiao Zhou, Zhong-Tao Liu, Yu Wen, Zi-Jian Zhang, Heng Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.723488/full