An In Vitro System to Study the Effect of Subchondral Bone Health on Articular Cartilage Repair in Humans

An In Vitro System to Study the Effect of Subchondral Bone Health on Articular Cartilage Repair in Humans

Chondrocyte-based cartilage repair strategies, such as articular chondrocyte implantation, are widely used, but few studies addressed the communication between native subchondral bone cells and the transplanted chondrocytes. An indirect co-culture model was developed, representing a chondrocyte/scaf...

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Bibliographic Details
Main Authors: Timothy Hopkins, Karina T. Wright, Nicola J. Kuiper, Sally Roberts, Paul Jermin, Peter Gallacher, Jan Herman Kuiper
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
cartilage repair
human
osteoarthritis
chondrocytes
bone-marrow-derived mesenchymal stromal cells (BM-MSCs)
co-culture
Online Access:https://www.mdpi.com/2073-4409/10/8/1903

Internet

https://www.mdpi.com/2073-4409/10/8/1903

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