SIAH ubiquitin E3 ligases as modulators of inflammatory gene expression

SIAH ubiquitin E3 ligases as modulators of inflammatory gene expression

The functionally redundant ubiquitin E3 ligases SIAH1 and SIAH2 have been implicated in the regulation of metabolism and the hypoxic response, while their role in other signal-mediated processes such inflammatory gene expression remains to be defined. Here we have downregulated the expression of bot...

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Bibliographic Details
Main Authors: M. Lienhard Schmitz, Jan Dreute, Maximilian Pfisterer, Stefan Günther, Michael Kracht, Shashipavan Chillappagari
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Heliyon
Subjects:
SIAH1
SIAH2
Ubiquitin E3 ligase
NF-κB
Inflammatory gene expression
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022003176

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http://www.sciencedirect.com/science/article/pii/S2405844022003176

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