Integration of immunoinformatics and cheminformatics to design and evaluate a multitope vaccine against Klebsiella pneumoniae and Pseudomonas aeruginosa coinfection

Integration of immunoinformatics and cheminformatics to design and evaluate a multitope vaccine against Klebsiella pneumoniae and Pseudomonas aeruginosa coinfection

Introduction:Klebsiella pneumoniae (K. pneumoniae) and Pseudomonas aeruginosa (P. aeruginosa) are the most common Gram-negative bacteria associated with pneumonia and coinfecting the same patient. Despite their high virulence, there is no effective vaccine against them.Methods: In the current study,...

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Bibliographic Details
Main Authors: Ahmed M. Gouda, Mohamed A. Soltan, Khalid Abd-Elghany, Ashraf E. Sileem, Hanan M. Elnahas, Marwa Abdel-Monem Ateya, Mahmoud H. Elbatreek, Khaled M. Darwish, Hanin A. Bogari, Manar O. Lashkar, Mohammed M. Aldurdunji, Sameh S. Elhady, Tarek A. Ahmad, Ahmed Mohamed Said
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
Klebsiella pneumoniae
Pseudomonas aeruginosa
immunoinformatics
multitope vaccine
industries development
drug discovery
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1123411/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2023.1123411/full

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