Vascular-water-exchange MRI (VEXI) enables the detection of subtle AXR alterations in Alzheimer's disease without MRI contrast agent, which may relate to BBB integrity

Vascular-water-exchange MRI (VEXI) enables the detection of subtle AXR alterations in Alzheimer's disease without MRI contrast agent, which may relate to BBB integrity

Abstracts: Blood-brain barrier (BBB) impairment is an important pathophysiological process in Alzheimer's disease (AD) and a potential biomarker for early diagnosis of AD. However, most current neuroimaging methods assessing BBB function need the injection of exogenous contrast agents (or trace...

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Bibliographic Details
Main Authors: Yifan Zhang, Yue Wang, Zhaoqing Li, Zejun Wang, Juange Cheng, Xiaoyan Bai, Yi-Cheng Hsu, Yi Sun, Shiping Li, Jiong Shi, Binbin Sui, Ruiliang Bai
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:NeuroImage
Subjects:
Blood-brain barrier
contrast-agent-free
water exchange
Alzheimer's disease
permeability
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811923000976

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http://www.sciencedirect.com/science/article/pii/S1053811923000976

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