Astragalus Polysaccharide Reduces Blood Pressure, Renal Damage, and Dysfunction Through the TGF-β1-ILK Pathway

Astragalus Polysaccharide Reduces Blood Pressure, Renal Damage, and Dysfunction Through the TGF-β1-ILK Pathway

Background:Astragalus polysaccharide extract (APS) has been shown to exhibit antioxidant and anti-inflammatory potential in the treatment of several diseases. However, whether APS could protect against renal damage in hypertensive mice is unknown.Methods: Hematoxylin and eosin staining, immunohistoc...

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Bibliographic Details
Main Authors: Wei Zheng, Tao Huang, Qi-Zhen Tang, Shi Li, Jie Qin, Feng Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Pharmacology
Subjects:
Astragalus polysaccharides
hypertension
transforming growth factor-β
integrin linked kinase
renal damage
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.706617/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.706617/full

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