Impact of Antigen Presentation Mechanisms on Immune Response in Autoimmune Hepatitis

The liver is a very tolerogenic organ. It is continually exposed to a multitude of antigens and is able to promote an effective immune response against pathogens and simultaneously immune tolerance against self-antigens. In spite of strong peripheral and central tolerogenic mechanisms, loss of toler...

Full description

Bibliographic Details
Main Authors: Rossella Fasano, Eleonora Malerba, Marcella Prete, Antonio Giovanni Solimando, Alessio Buonavoglia, Nicola Silvestris, Patrizia Leone, Vito Racanelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.814155/full