Variability and efficacy in treatment effects on manic symptoms with lithium, anticonvulsants, and antipsychotics in acute bipolar mania: A systematic review and meta-analysis

Variability and efficacy in treatment effects on manic symptoms with lithium, anticonvulsants, and antipsychotics in acute bipolar mania: A systematic review and meta-analysis

Summary: Background: Acute mania is a psychiatric emergency requiring rapid management. However, randomised controlled trials (RCTs) have shown considerable individual differences in treatment effects on manic symptoms with antimanic drugs. Methods: We searched the MEDLINE, CENTRAL, EMBASE, PsycINF...

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Bibliographic Details
Main Authors: Tien-Wei Hsu, Trevor Thompson, Marco Solmi, Eduard Vieta, Fu-Chi Yang, Ping-Tao Tseng, Chih-Wei Hsu, Yu-Kang Tu, Chia-Ling Yu, Chia-Kuang Tsai, Chih-Sung Liang, Andre F. Carvalho
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:EClinicalMedicine
Subjects:
Bipolar mania
Variability in improvement of manic symptoms
Meta-analysis
Antipsychotics
Mood stabilisers
Anticonvulsants
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537022004205

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http://www.sciencedirect.com/science/article/pii/S2589537022004205

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