Inositol hexakisphosphate-induced autoprocessing of large bacterial protein toxins.

Large bacterial protein toxins autotranslocate functional effector domains to the eukaryotic cell cytosol, resulting in alterations to cellular functions that ultimately benefit the infecting pathogen. Among these toxins, the clostridial glucosylating toxins (CGTs) produced by Gram-positive bacteria...

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Bibliographic Details
Main Authors: Martina Egerer, Karla J F Satchell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2900308?pdf=render