Identification of peripheral vascular function measures and circulating biomarkers of mitochondrial function in patients with mitochondrial disease

Abstract The development of pharmacological therapies for mitochondrial diseases is hampered by the lack of tissue‐level and circulating biomarkers reflecting effects of compounds on endothelial and mitochondrial function. This phase 0 study aimed to identify biomarkers differentiating between patie...

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Bibliographic Details
Main Authors: Sebastiaan J. W. vanKraaij, Diana R. Pereira, Bastiaan Smal, Luciana Summo, Anne Konkel, Janine Lossie, Andreas Busjahn, Tom N. Grammatopoulos, Erica Klaassen, Robert Fischer, Wolf‐Hagen Schunck, Pim Gal, Matthijs Moerland
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.13530