Voltammetric Sensors Based on Nanomaterials for Detection of Caffeic Acid in Food Supplements
Caffeic acid may be accurately detected in food supplements by using cyclic voltammetry and carbon screen-printed sensors modified with various nanomaterials. Sensor characterization by cyclic voltammetry in reference solutions has shown that carbon nanotubes or carbon nanofibers significantly impro...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-06-01
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| Series: | Chemosensors |
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| Online Access: | https://www.mdpi.com/2227-9040/8/2/41 |
| _version_ | 1797564820256456704 |
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| author | Alexandra Virginia Bounegru Constantin Apetrei |
| author_facet | Alexandra Virginia Bounegru Constantin Apetrei |
| author_sort | Alexandra Virginia Bounegru |
| collection | DOAJ |
| description | Caffeic acid may be accurately detected in food supplements by using cyclic voltammetry and carbon screen-printed sensors modified with various nanomaterials. Sensor characterization by cyclic voltammetry in reference solutions has shown that carbon nanotubes or carbon nanofibers significantly improve the sensor response in terms of sensitivity and reversibility. Screen-printed sensors were then used in order to study the electrochemical behavior of caffeic acid in aqueous solution at pH 3.6. A redox process was observed in all cases, which corresponds to a reversible redox process involving the transfer of two electrons and two protons. The role of nanomaterials in the increment of sensor performance characteristics was evidenced. Calibration curves were developed for each sensor, and the detection (LOD) and quantification (LOQ) limits were calculated. Low LOD and LOQ values were obtained, in the 10<sup>−7</sup> to 10<sup>−9</sup> M range, which demonstrates that the method is feasible for quantification of caffeic acid in real samples. Caffeic acid was quantitatively determined in three food supplements using the most sensitive sensor, namely the carbon nanofiber sensor. The Folin–Ciocalteu spectrophotometric assay was used to validate the results obtained with the sensor. The results obtained by using the voltammetric method were consistent with those obtained by using the spectrophotometric method, with no statistically significant differences between the results obtained at 95% confidence level. |
| first_indexed | 2024-03-10T19:03:22Z |
| format | Article |
| id | doaj.art-994d82aadff942198a490a3d3cb665c4 |
| institution | Directory Open Access Journal |
| issn | 2227-9040 |
| language | English |
| last_indexed | 2024-03-10T19:03:22Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Chemosensors |
| spelling | doaj.art-994d82aadff942198a490a3d3cb665c42023-11-20T04:17:36ZengMDPI AGChemosensors2227-90402020-06-01824110.3390/chemosensors8020041Voltammetric Sensors Based on Nanomaterials for Detection of Caffeic Acid in Food SupplementsAlexandra Virginia Bounegru0Constantin Apetrei1Department of Chemistry, Physics and Environment, Faculty of Sciences and Environment, “Dunărea de Jos” University of Galaţi, 47 Domnească Street, 800008 Galaţi, RomaniaDepartment of Chemistry, Physics and Environment, Faculty of Sciences and Environment, “Dunărea de Jos” University of Galaţi, 47 Domnească Street, 800008 Galaţi, RomaniaCaffeic acid may be accurately detected in food supplements by using cyclic voltammetry and carbon screen-printed sensors modified with various nanomaterials. Sensor characterization by cyclic voltammetry in reference solutions has shown that carbon nanotubes or carbon nanofibers significantly improve the sensor response in terms of sensitivity and reversibility. Screen-printed sensors were then used in order to study the electrochemical behavior of caffeic acid in aqueous solution at pH 3.6. A redox process was observed in all cases, which corresponds to a reversible redox process involving the transfer of two electrons and two protons. The role of nanomaterials in the increment of sensor performance characteristics was evidenced. Calibration curves were developed for each sensor, and the detection (LOD) and quantification (LOQ) limits were calculated. Low LOD and LOQ values were obtained, in the 10<sup>−7</sup> to 10<sup>−9</sup> M range, which demonstrates that the method is feasible for quantification of caffeic acid in real samples. Caffeic acid was quantitatively determined in three food supplements using the most sensitive sensor, namely the carbon nanofiber sensor. The Folin–Ciocalteu spectrophotometric assay was used to validate the results obtained with the sensor. The results obtained by using the voltammetric method were consistent with those obtained by using the spectrophotometric method, with no statistically significant differences between the results obtained at 95% confidence level.https://www.mdpi.com/2227-9040/8/2/41caffeic acidcyclic voltammetrycarbon nanofiberscarbon nanotubessensor |
| spellingShingle | Alexandra Virginia Bounegru Constantin Apetrei Voltammetric Sensors Based on Nanomaterials for Detection of Caffeic Acid in Food Supplements Chemosensors caffeic acid cyclic voltammetry carbon nanofibers carbon nanotubes sensor |
| title | Voltammetric Sensors Based on Nanomaterials for Detection of Caffeic Acid in Food Supplements |
| title_full | Voltammetric Sensors Based on Nanomaterials for Detection of Caffeic Acid in Food Supplements |
| title_fullStr | Voltammetric Sensors Based on Nanomaterials for Detection of Caffeic Acid in Food Supplements |
| title_full_unstemmed | Voltammetric Sensors Based on Nanomaterials for Detection of Caffeic Acid in Food Supplements |
| title_short | Voltammetric Sensors Based on Nanomaterials for Detection of Caffeic Acid in Food Supplements |
| title_sort | voltammetric sensors based on nanomaterials for detection of caffeic acid in food supplements |
| topic | caffeic acid cyclic voltammetry carbon nanofibers carbon nanotubes sensor |
| url | https://www.mdpi.com/2227-9040/8/2/41 |
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