Single cell in vivo optogenetic stimulation by two-photon excitation fluorescence transfer

Summary: Optogenetic manipulation with single-cell resolution can be achieved by two-photon excitation. However, this frequently requires relatively high laser powers. Here, we developed a novel strategy that can improve the efficiency of current two-photon stimulation technologies by positioning fl...

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Bibliographic Details
Main Authors: Lei Tong, Shanshan Han, Yao Xue, Minggang Chen, Fuyi Chen, Wei Ke, Yousheng Shu, Ning Ding, Joerg Bewersdorf, Z. Jimmy Zhou, Peng Yuan, Jaime Grutzendler
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422301934X