Endo-lysosomal assembly variations among human leukocyte antigen class I (HLA class I) allotypes
The extreme polymorphisms of human leukocyte antigen class I (HLA class I) proteins enable the presentation of diverse peptides to cytotoxic T lymphocytes. The canonical endoplasmic reticulum (ER) HLA class I assembly pathway enables presentation of cytosolic peptides, but effective intracellular su...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2023-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/79144 |