Medicarpin and Homopterocarpin Isolated from <i>Canavalia lineata</i> as Potent and Competitive Reversible Inhibitors of Human Monoamine Oxidase-B

Medicarpin and Homopterocarpin Isolated from <i>Canavalia lineata</i> as Potent and Competitive Reversible Inhibitors of Human Monoamine Oxidase-B

Thirteen compounds were isolated from the <i>Canavalia lineata</i> pods and their inhibitory activities against human monoamine oxidase-A (hMAO-A) and -B (hMAO-B) were evaluated. Among them, compounds <b>8</b> (medicarpin) and <b>13</b> (homopterocarpin) showed po...

Full description

Bibliographic Details
Main Authors: Jong Min Oh, Hyun-Jae Jang, Myung-Gyun Kang, Seul-Ki Mun, Daeui Park, Su-Jin Hong, Min Ha Kim, Soo-Young Kim, Sung-Tae Yee, Hoon Kim
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
<i>Canavalia lineata</i>
medicarpin
homopterocarpin
selective human monoamine oxidase-B inhibitor
docking simulation
Online Access:https://www.mdpi.com/1420-3049/28/1/258

Internet

https://www.mdpi.com/1420-3049/28/1/258

Similar Items