Tissue distribution and integrated pharmacokinetic properties of major effective constituents of oral Gegen-Qinlian decoction in mice

Tissue distribution and integrated pharmacokinetic properties of major effective constituents of oral Gegen-Qinlian decoction in mice

Gegen-Qinlian decoction (GQD) is a classic traditional Chinese medicine (TCM) formula. GQD is effective against colon or liver-related diseases including ulcerative colitis, non-alcoholic fatty liver, and type 2 diabetes. In this study, a liquid chromatography-tandem mass spectrometry method was dev...

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Bibliographic Details
Main Authors: Jing-Ze Lu, Dan-Dan Hong, Dan Ye, Sheng Mu, Rong Shi, Yu Song, Chu Feng, Bing-Liang Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
gegen-qinlian decoction
effective constituents
integrated pharmacokinetics
tissue distribution
LC-MS/MS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.996143/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.996143/full

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