Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy

Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy

Abstract Background Diabetic nephropathy (DN) involves various structural and functional changes because of chronic glycemic assault and kidney failure. Proteinuria is an early clinical manifestation of DN, but the associated pathogenesis remains elusive. This study aimed to investigate the role of...

Full description

Bibliographic Details
Main Authors: Lingfei Li, Yanhai Feng, Junhui Zhang, Qiong Zhang, Jun Ren, Cheng Sun, Shujing Li, Xia Lei, Gaoxing Luo, Jiongyu Hu, Yuesheng Huang
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Cell Communication and Signaling
Subjects:
MAP4
Diabetic nephropathy
Proteinuria
Epithelial-to-mesenchymal transition
Apoptosis
Online Access:https://doi.org/10.1186/s12964-022-00883-7

Internet

https://doi.org/10.1186/s12964-022-00883-7

Similar Items