Incorporation of Low Concentrations of Gold Nanoparticles: Complex Effects on Radiation Response and Fate of Cancer Cells

Incorporation of Low Concentrations of Gold Nanoparticles: Complex Effects on Radiation Response and Fate of Cancer Cells

<b>(1) Background</b>: In oncology research, a long-standing discussion exists about pros and cons of metal nanoparticle-enhanced radiotherapy and real mechanisms behind the tumor cell response to irradiation (IR) in presence of gold nanoparticles (GNPs). A better understanding of this r...

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Bibliographic Details
Main Authors: Lucie Dobešová, Theresa Gier, Olga Kopečná, Eva Pagáčová, Tomáš Vičar, Felix Bestvater, Jiří Toufar, Alena Bačíková, Pavel Kopel, Radek Fedr, Georg Hildenbrand, Iva Falková, Martin Falk, Michael Hausmann
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pharmaceutics
Subjects:
gold nanoparticles (GNP)
nanoparticle-enhanced cancer radiotherapy
DNA double strand breaks (DSBs)
DNA repair
chromatin nano-architecture rearrangements
single-molecule localization microscopy (SMLM)
Online Access:https://www.mdpi.com/1999-4923/14/1/166

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https://www.mdpi.com/1999-4923/14/1/166

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