Corosolic Acid Protects Rat Chondrocytes Against IL-1β-Induced ECM Degradation by Activating Autophagy via PI3K/AKT/mTOR Pathway and Ameliorates Rat Osteoarthritis

Corosolic Acid Protects Rat Chondrocytes Against IL-1β-Induced ECM Degradation by Activating Autophagy via PI3K/AKT/mTOR Pathway and Ameliorates Rat Osteoarthritis

Hui Han,1– 3,* Ming Chen,2,* Zhenyu Li,2,* Siqi Zhou,2 Yingbin Wu,3 Jian Wei1 1Department of Sports Medicine and Joint Orthopedics, Liuzhou People’s Hospital, Liuzhou, Guangxi, People’s Republic of China; 2Department of Orthopedic Surgery, Zhongnan Hospital of Wuhan Universit...

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Bibliographic Details
Main Authors: Han H, Chen M, Li Z, Zhou S, Wu Y, Wei J
Format: Article
Language:English
Published: Dove Medical Press 2022-08-01
Series:Drug Design, Development and Therapy
Subjects:
osteoarthritis
corosolic acid
autophagy
extracellular matrix
pi3k/akt/mtor signaling
Online Access:https://www.dovepress.com/corosolic-acid-protects-rat-chondrocytes-against-il-1-induced-ecm-degr-peer-reviewed-fulltext-article-DDDT

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https://www.dovepress.com/corosolic-acid-protects-rat-chondrocytes-against-il-1-induced-ecm-degr-peer-reviewed-fulltext-article-DDDT

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