Antibiotics Drive Expansion of Rare Pathogens in a Chronic Infection Microbiome Model

Antibiotics Drive Expansion of Rare Pathogens in a Chronic Infection Microbiome Model

ABSTRACT Chronic (long-lasting) infections are globally a major and rising cause of morbidity and mortality. Unlike typical acute infections, chronic infections are ecologically diverse, characterized by the presence of a polymicrobial mix of opportunistic pathogens and human-associated commensals....

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Bibliographic Details
Main Authors: John J. Varga, Conan Y. Zhao, Jacob D. Davis, Yiqi Hao, Jennifer M. Farrell, James R. Gurney, Eberhard Voit, Sam P. Brown
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:mSphere
Subjects:
antibiotic resistance
chronic infection
cystic fibrosis
experimental microbiome
infection microbiome
Online Access:https://journals.asm.org/doi/10.1128/msphere.00318-22

Internet

https://journals.asm.org/doi/10.1128/msphere.00318-22

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