The double protonation of dihapto-coordinated benzene complexes enables dearomatization using aromatic nucleophiles

Abstract Friedel-Crafts Arylation (the Scholl reaction) is the coupling of two aromatic rings with the aid of a strong Lewis or Brønsted acid. This historically significant C–C bond forming reaction normally leads to aromatic products, often as oligomeric mixtures, dictated by the large stabilizatio...

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Bibliographic Details
Main Authors: Justin T. Weatherford-Pratt, Jacob A. Smith, Jeremy M. Bloch, Megan N. Ericson, Jeffery T. Myers, Karl S. Westendorff, Diane A. Dickie, W. Dean Harman
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38945-0