Development and validation of bioanalytical UHPLC-UV method for simultaneous analysis of unchanged fenofibrate and its metabolite fenofibric acid in rat plasma: Application to pharmacokinetics

Development and validation of bioanalytical UHPLC-UV method for simultaneous analysis of unchanged fenofibrate and its metabolite fenofibric acid in rat plasma: Application to pharmacokinetics

A simple, precise, selective and fast ultra-high performance liquid chromatography (UHPLC-UV) method has been developed and validated for the simultaneous determination of a lipid regulating agent fenofibrate and its metabolite fenofibric acid in rat plasma. The chromatographic separation was carrie...

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Bibliographic Details
Main Authors: Rayan G. Alamri, Kazi Mohsin, Ajaz Ahmad, Mohammad Raish, Fars K. Alanazi
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Saudi Pharmaceutical Journal
Subjects:
Fenofibrate
Fenofibric acid
Method validation
RP-UHPLC
Pharmacokinetics
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016416300470

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http://www.sciencedirect.com/science/article/pii/S1319016416300470

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